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Catalog: YT4409
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Main Information
Target

SR-7

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

IF, ELISA

MW

54kD (Calculated)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications;
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
SR-7 Polyclonal Antibody detects endogenous levels of SR-7 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
54kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human HTR7. AA range:391-440
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Specificity:
SR-7 Polyclonal Antibody detects endogenous levels of SR-7 protein.
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Gene Name:
HTR7
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Protein Name:
5-hydroxytryptamine receptor 7
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Other Name:
HTR7 ;
5-hydroxytryptamine receptor 7 ;
5-HT-7 ;
5-HT7 ;
5-HT-X ;
Serotonin receptor 7
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Database Link:
Organism Gene ID SwissProt
Human 3363; P34969;
Mouse 15566; P32304;
Rat 65032; P32305;
Background:
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008],
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Function:
Alternative products:Isoform A and isoform B appear to be expressed at higher levels,Function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels, and isoform D is a minor isoform.,
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Research Areas:
>>Ras signaling pathway ;
>>Calcium signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Serotonergic synapse
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Catalog: YT4409
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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