Catalog: YT4013
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
RASSF6
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
WB, ELISA
MW
45kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
RASSF6 Polyclonal Antibody detects endogenous levels of RASSF6 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
45kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human RASSF6. AA range:129-178
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Specificity:
RASSF6 Polyclonal Antibody detects endogenous levels of RASSF6 protein.
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Gene Name:
RASSF6
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Protein Name:
Ras association domain-containing protein 6
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Other Name:
RASSF6 ;
Ras association domain-containing protein 6
Ras association domain-containing protein 6
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Background:
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012],
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Function:
Function:May act as a Ras effector protein.,sequence Caution:Translated as Gln.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,
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Tissue Expression:
Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart.
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Research Areas:
>>Hippo signaling pathway ;
>>Hippo signaling pathway - multiple species
>>Hippo signaling pathway - multiple species
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT4013
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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