Catalog: YT3947
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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0
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Main Information
Target
Rabaptin-5α
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
99kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Rabaptin-5α Polyclonal Antibody detects endogenous levels of Rabaptin-5α protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
99kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human RABEP1. AA range:549-598
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Specificity:
Rabaptin-5α Polyclonal Antibody detects endogenous levels of Rabaptin-5α protein.
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Gene Name:
RABEP1
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Protein Name:
Rab GTPase-binding effector protein 1
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Other Name:
RABEP1 ;
RAB5EP ;
RABPT5 ;
RABPT5A ;
Rab GTPase-binding effector protein 1 ;
Rabaptin-4 ;
Rabaptin-5 ;
Rabaptin-5alpha ;
Renal carcinoma antigen NY-REN-17
RAB5EP ;
RABPT5 ;
RABPT5A ;
Rab GTPase-binding effector protein 1 ;
Rabaptin-4 ;
Rabaptin-5 ;
Rabaptin-5alpha ;
Renal carcinoma antigen NY-REN-17
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Database Link:
Background:
function:Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.,PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.,
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Function:
Function:Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.,PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.,
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Cellular Localization:
Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle.
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Tissue Expression:
Cervix carcinoma,Epithelium,Fetal brain cortex,Kidney,Plate
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Research Areas:
>>Endocytosis
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Reference Citation({{totalcount}})
Catalog: YT3947
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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