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Main Information
Target
Rab 11B
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW
28kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Rab 11B Polyclonal Antibody detects endogenous levels of Rab 11B protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
28kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human RAB11B. AA range:164-213
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Specificity:
Rab 11B Polyclonal Antibody detects endogenous levels of Rab 11B protein.
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Gene Name:
RAB11B
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Protein Name:
Ras-related protein Rab-11B
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Other Name:
RAB11B ;
YPT3 ;
Ras-related protein Rab-11B ;
GTP-binding protein YPT3
YPT3 ;
Ras-related protein Rab-11B ;
GTP-binding protein YPT3
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Database Link:
Background:
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010],
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Function:
Function:Possesses GTPase activity.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4.,
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Cellular Localization:
Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus. .
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Tissue Expression:
B-cell lymphoma,Brain,Cerebellum,Muscle,
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Research Areas:
>>Endocytosis ;
>>AMPK signaling pathway ;
>>Vasopressin-regulated water reabsorption ;
>>Influenza A
>>AMPK signaling pathway ;
>>Vasopressin-regulated water reabsorption ;
>>Influenza A
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Catalog: YT3919
Size
Price
Status
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200μL
$450.00
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100μL
$280.00
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40μL
$150.00
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