Catalog: YT3881
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
PSGR
Host Species
Rabbit
Reactivity
Human, Rat
Applications
WB, IF, ELISA, IHC
MW
35kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300; IF 1:200-1:1000; ELISA 1:2000-20000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
PSGR Polyclonal Antibody detects endogenous levels of PSGR protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
35kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human OR51E2. AA range:221-270
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Specificity:
PSGR Polyclonal Antibody detects endogenous levels of PSGR protein.
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Gene Name:
OR51E2
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Protein Name:
Olfactory receptor 51E2
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Other Name:
OR51E2 ;
PSGR ;
Olfactory receptor 51E2 ;
HPRAJ ;
Olfactory receptor OR11-16 ;
Prostate-specific G-protein coupled receptor
PSGR ;
Olfactory receptor 51E2 ;
HPRAJ ;
Olfactory receptor OR11-16 ;
Prostate-specific G-protein coupled receptor
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Background:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],
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Function:
Function:Odorant receptor .,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Exclusively expressed in the prostate. Up-regulated in prostate cancers.,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein .
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Tissue Expression:
Highly expressed in the prostate (PubMed:11707321). Also expressed in spleen, liver, olfactory epithelium, retinal pigment epithelium and medulla oblongata (PubMed:29249973, PubMed:11707321, PubMed:16491480). In the retinal pigment epithelium expression is restricted to the pigment cells and choroid (at protein level) (PubMed:29249973). Expressed in epidermal melanocytes (at protein level) (PubMed:27226631).
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Research Areas:
>>Olfactory transduction
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Reference Citation({{totalcount}})
Catalog: YT3881
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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