Catalog: YT3564
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
PABP5
Host Species
Rabbit
Reactivity
Human
Applications
WB, IHC, IF, ELISA
MW
43kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
PABP5 Polyclonal Antibody detects endogenous levels of PABP5 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
43kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human PABPC5. AA range:184-233
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Specificity:
PABP5 Polyclonal Antibody detects endogenous levels of PABP5 protein.
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Gene Name:
PABPC5
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Protein Name:
Polyadenylate-binding protein 5
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Other Name:
PABPC5 ;
PABP5 ;
Polyadenylate-binding protein 5 ;
PABP-5 ;
Poly ;
A ;
-binding protein 5
PABP5 ;
Polyadenylate-binding protein 5 ;
PABP-5 ;
Poly ;
A ;
-binding protein 5
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Background:
This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010],
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Function:
Function:Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Expressed in fetal brain and in a range of adult tissues.,
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Cellular Localization:
Cytoplasm .; [Isoform 2]: Mitochondrion matrix . Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly(A) polymerase.
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Tissue Expression:
Expressed in fetal brain and in a range of adult tissues.
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Research Areas:
>>mRNA surveillance pathway ;
>>RNA degradation
>>RNA degradation
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT3564
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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