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Catalog: YT3476
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Main Information
Target

OTUD2

Host Species

Rabbit

Reactivity

Human, Rat, Mouse,

Applications

WB, ELISA

MW

35kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
OTUD2 Polyclonal Antibody detects endogenous levels of OTUD2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
35kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human YOD1. AA range:116-165
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Specificity:
OTUD2 Polyclonal Antibody detects endogenous levels of OTUD2 protein.
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Gene Name:
YOD1
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Protein Name:
Ubiquitin thioesterase OTU1
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Other Name:
YOD1 ;
DUBA8 ;
HIN7 ;
OTUD2 ;
Ubiquitin thioesterase OTU1 ;
DUBA-8 ;
HIV-1-induced protease 7 ;
HIN-7 ;
HsHIN7 ;
OTU domain-containing protein 2
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Database Link:
Organism Gene ID SwissProt
Human 55432; Q5VVQ6;
Mouse Q8CB27;
Background:
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
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Function:
Function:Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.,sequence Caution:Wrong choice of frame.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 OTU domain.,
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Cellular Localization:
Cytoplasm . Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains. .
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Tissue Expression:
Fetal liver,Spinal cord,Testis,
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Research Areas:
>>Protein processing in endoplasmic reticulum
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Catalog: YT3476
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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