Catalog: YT3471
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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0
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Main Information
Target
Orexin R-1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
50kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Orexin R-1 Polyclonal Antibody detects endogenous levels of Orexin R-1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
50kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human HCRTR1. AA range:231-280
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Specificity:
Orexin R-1 Polyclonal Antibody detects endogenous levels of Orexin R-1 protein.
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Gene Name:
HCRTR1
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Protein Name:
Orexin receptor type 1
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Other Name:
HCRTR1 ;
Orexin receptor type 1 ;
Ox-1-R ;
Ox1-R ;
Ox1R ;
Hypocretin receptor type 1
Orexin receptor type 1 ;
Ox-1-R ;
Ox1-R ;
Ox1R ;
Hypocretin receptor type 1
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Database Link:
Background:
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009],
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Function:
Function:Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein .
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Tissue Expression:
Brain,
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Research Areas:
>>Neuroactive ligand-receptor interaction
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Reference Citation({{totalcount}})
Catalog: YT3471
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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