Catalog: YT3237
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
O-FucT-1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
44kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
O-FucT-1 Polyclonal Antibody detects endogenous levels of O-FucT-1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
44kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human POFUT1. AA range:331-380
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Specificity:
O-FucT-1 Polyclonal Antibody detects endogenous levels of O-FucT-1 protein.
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Gene Name:
POFUT1
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Protein Name:
GDP-fucose protein O-fucosyltransferase 1
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Other Name:
POFUT1 ;
FUT12 ;
KIAA0180 ;
GDP-fucose protein O-fucosyltransferase 1 ;
Peptide-O-fucosyltransferase 1 ;
O-FucT-1
FUT12 ;
KIAA0180 ;
GDP-fucose protein O-fucosyltransferase 1 ;
Peptide-O-fucosyltransferase 1 ;
O-FucT-1
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Database Link:
Background:
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
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Function:
Catalytic activity:Transfers an alpha-L-fucosyl residue from GDP-beta-L-fucose to the serine hydroxy group of a protein acceptor.,cofactor:Manganese.,Function:Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in EGF domains. Plays a crucial role in Notch signaling.,online information:GlycoGene database,online information:Peptide-O-fucosyltransferase 1,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 68 family.,tissue specificity:Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
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Cellular Localization:
Endoplasmic reticulum .
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Tissue Expression:
Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
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Research Areas:
>>Other types of O-glycan biosynthesis
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Reference Citation({{totalcount}})
Catalog: YT3237
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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