Catalog: YT3185
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
NPY5-R
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
48kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
NPY5-R Polyclonal Antibody detects endogenous levels of NPY5-R protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
48kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human NPY5R. AA range:221-270
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Specificity:
NPY5-R Polyclonal Antibody detects endogenous levels of NPY5-R protein.
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Gene Name:
NPY5R
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Protein Name:
Neuropeptide Y receptor type 5
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Other Name:
NPY5R ;
NPYR5 ;
Neuropeptide Y receptor type 5 ;
NPY5-R ;
NPY-Y5 receptor ;
NPYY5-R ;
Y5 receptor
NPYR5 ;
Neuropeptide Y receptor type 5 ;
NPY5-R ;
NPY-Y5 receptor ;
NPYY5-R ;
Y5 receptor
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Database Link:
Background:
The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015],
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Function:
Function:Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Brain; hypothalamus.,
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Tissue Expression:
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Research Areas:
>>Neuroactive ligand-receptor interaction
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Reference Citation({{totalcount}})
Catalog: YT3185
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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