Catalog: YT3027
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
NEDL2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
140-150kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
NEDL2 Polyclonal Antibody detects endogenous levels of NEDL2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
140-150kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530
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Specificity:
NEDL2 Polyclonal Antibody detects endogenous levels of NEDL2 protein.
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Gene Name:
HECW2
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Protein Name:
E3 ubiquitin-protein ligase HECW2
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Other Name:
HECW2 ;
KIAA1301 ;
NEDL2 ;
E3 ubiquitin-protein ligase HECW2 ;
HECT ;
C2 and WW domain-containing protein 2 ;
NEDD4-like E3 ubiquitin-protein ligase 2
KIAA1301 ;
NEDL2 ;
E3 ubiquitin-protein ligase HECW2 ;
HECT ;
C2 and WW domain-containing protein 2 ;
NEDD4-like E3 ubiquitin-protein ligase 2
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Background:
function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with TP73.,tissue specificity:Predominantly expressed in adult brain, lung and heart.,
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Function:
Function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with TP73.,tissue specificity:Predominantly expressed in adult brain, lung and heart.,
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Cellular Localization:
Cytoplasm . Cytoplasm, cytoskeleton, spindle .
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Tissue Expression:
Predominantly expressed in adult brain, lung and heart.
show all
Reference Citation({{totalcount}})
Catalog: YT3027
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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