Synthesized peptide derived from Ndfip1 . at AA range: 150-230

Ndfip1 Polyclonal Antibody detects endogenous levels of Ndfip1 protein.

NDFIP1

NEDD4 family-interacting protein 1

NDFIP1 ;
N4WBP5 ;
PSEC0192 ;
PSEC0223 ;
NEDD4 family-interacting protein 1 ;
Breast cancer-associated protein SGA-1M ;
NEDD4 WW domain-binding protein 5 ;
Putative MAPK-activating protein PM13 ;
Putative NF-kappa-B-activating protein 164 ;
Putative

The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins. [provided by RefSeq, Jul 2008],

developmental stage:Expressed in fetal brain, kidney and lung.,Domain:The WW-binding motifs mediate interaction with NEDD4.,Function:May play a role in Golgi structure maintenance.,PTM:Ubiquitinated by NEDD4; mono-, di- and polyubiquitinated forms are detected. Ubiquitination regulates its degradation.,subunit:Interacts with NEDD4. Interacts in vitro with NEDD4L, SR140, WWP2 and ITCH.,tissue specificity:Widely expressed. Higher levels are detected in cerebellum, pituitary, thalamus, kidney, liver, testis, salivary glands and placenta.,

Endosome membrane ; Multi-pass membrane protein . Golgi apparatus membrane . Cell junction, synapse, synaptosome . Cell projection, dendrite . Secreted . Detected in exosomes and secreted via the exosomal pathway (PubMed:18819914).

Widely expressed. Higher levels are detected in cerebellum, pituitary, thalamus, kidney, liver, testis, salivary glands and placenta. Also expressed in fetal brain, kidney and lung.