Catalog: YT2600
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
L-type Ca++ CP γ7
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
40kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
L-type Ca++ CP γ7 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ7 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
40kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human CACNG7. AA range:198-247
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Specificity:
L-type Ca++ CP γ7 Polyclonal Antibody detects endogenous levels of L-type Ca++ CP γ7 protein.
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Gene Name:
CACNG7
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Protein Name:
Voltage-dependent calcium channel gamma-7 subunit
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Other Name:
CACNG7 ;
Voltage-dependent calcium channel gamma-7 subunit ;
Neuronal voltage-gated calcium channel gamma-7 subunit ;
Transmembrane AMPAR regulatory protein gamma-7 ;
TARP gamma-7
Voltage-dependent calcium channel gamma-7 subunit ;
Neuronal voltage-gated calcium channel gamma-7 subunit ;
Transmembrane AMPAR regulatory protein gamma-7 ;
TARP gamma-7
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Database Link:
Background:
calcium voltage-gated channel auxiliary subunit gamma 7(CACNG7) Homo sapiens The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010],
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Function:
Function:Thought to stabilize the calcium channel in an inactivated (closed) state.,similarity:Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.,subunit:The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.,tissue specificity:Widely expressed.,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein .
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Tissue Expression:
Detected in heart left ventricle (PubMed:21127204). Widely expressed.
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Research Areas:
>>MAPK signaling pathway ;
>>Cardiac muscle contraction ;
>>Adrenergic signaling in cardiomyocytes ;
>>Oxytocin signaling pathway ;
>>Hypertrophic cardiomyopathy ;
>>Arrhythmogenic right ventricular cardiomyopathy ;
>>Dilated cardiomyopathy
>>Cardiac muscle contraction ;
>>Adrenergic signaling in cardiomyocytes ;
>>Oxytocin signaling pathway ;
>>Hypertrophic cardiomyopathy ;
>>Arrhythmogenic right ventricular cardiomyopathy ;
>>Dilated cardiomyopathy
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Signaling Pathway
Organismal Systems >> Endocrine system >> Oxytocin signaling pathway
Organismal Systems >> Circulatory system >> Cardiac muscle contraction
Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Reference Citation({{totalcount}})
Catalog: YT2600
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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