Catalog: YT1793
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
FRS3
Host Species
Rabbit
Reactivity
Human, Monkey
Applications
WB, ELISA
MW
54kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
FRS3 Polyclonal Antibody detects endogenous levels of FRS3 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
54kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human FRS3. AA range:191-240
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Specificity:
FRS3 Polyclonal Antibody detects endogenous levels of FRS3 protein.
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Gene Name:
FRS3
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Protein Name:
Fibroblast growth factor receptor substrate 3
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Other Name:
FRS3 ;
Fibroblast growth factor receptor substrate 3 ;
FGFR substrate 3 ;
FGFR-signaling adaptor SNT2 ;
Suc1-associated neurotrophic factor target 2 ;
SNT-2
Fibroblast growth factor receptor substrate 3 ;
FGFR substrate 3 ;
FGFR-signaling adaptor SNT2 ;
Suc1-associated neurotrophic factor target 2 ;
SNT-2
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Background:
This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013],
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Function:
Function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.,PTM:Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB.,similarity:Contains 1 IRS-type PTB domain.,subunit:Binds NTRK1 (By similarity). Binds FGFR1, NGFR, GRB2, PTPN11 and ERK2.,
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Cellular Localization:
Membrane; Lipid-anchor.
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Tissue Expression:
Brain,Placenta,
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Reference Citation({{totalcount}})
Catalog: YT1793
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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