Catalog: YT1658
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
FAF1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
75kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
FAF1 Polyclonal Antibody detects endogenous levels of FAF1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
75kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human FAF1. AA range:531-580
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Specificity:
FAF1 Polyclonal Antibody detects endogenous levels of FAF1 protein.
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Gene Name:
FAF1
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Protein Name:
FAS-associated factor 1
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Other Name:
FAF1 ;
UBXD12 ;
UBXN3A ;
CGI-03 ;
FAS-associated factor 1 ;
hFAF1 ;
UBX domain-containing protein 12 ;
UBX domain-containing protein 3A
UBXD12 ;
UBXN3A ;
CGI-03 ;
FAS-associated factor 1 ;
hFAF1 ;
UBX domain-containing protein 12 ;
UBX domain-containing protein 3A
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Database Link:
Background:
Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008],
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Function:
Function:Potentiates but cannot initiate FAS-induced apoptosis.,similarity:Contains 1 UBX domain.,subunit:Specifically interacts with the cytoplasmic domain of FAS.,tissue specificity:Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.
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Research Areas:
>>Necroptosis
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Reference Citation({{totalcount}})
Catalog: YT1658
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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