Catalog: YT1341
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
DHA Kinase
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
59kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:200-1:1000; ELISA 1:20000; IF 1:20-50
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
DHA Kinase Polyclonal Antibody detects endogenous levels of DHA Kinase protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
59kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human DAK. AA range:91-140
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Specificity:
DHA Kinase Polyclonal Antibody detects endogenous levels of DHA Kinase protein.
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Gene Name:
DAK
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Protein Name:
Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase
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Other Name:
DAK ;
Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase ;
cyclizing
Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase ;
cyclizing
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Database Link:
Background:
This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008],
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Function:
Catalytic activity:ATP + glycerone = ADP + glycerone phosphate.,Catalytic activity:FAD = AMP + riboflavin cyclic-4',5'-phosphate.,cofactor:Magnesium.,cofactor:Manganese or cobalt; for FAD-AMP lyase activity.,enzyme regulation:Each activity is inhibited by the substrate(s) of the other.,Function:Catalyzes both the phosphorylation of dihydroxyacetone and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate.,similarity:Belongs to the dihydroxyacetone kinase (DAK) family.,similarity:Contains 1 DAK1 (dihydroxyacetone kinase subunit 1) domain.,similarity:Contains 1 DAK2 (dihydroxyacetone kinase subunit 2) domain.,subunit:Homodimer.,
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Cellular Localization:
nucleus,cytosol,extracellular exosome,
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Tissue Expression:
Research Areas:
>>Fructose and mannose metabolism ;
>>Glycerolipid metabolism ;
>>Metabolic pathways ;
>>Carbon metabolism ;
>>RIG-I-like receptor signaling pathway
>>Glycerolipid metabolism ;
>>Metabolic pathways ;
>>Carbon metabolism ;
>>RIG-I-like receptor signaling pathway
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Reference Citation({{totalcount}})
Catalog: YT1341
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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