Catalog: YT0501
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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Main Information
Target
BMP-5
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
52kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
BMP-5 Polyclonal Antibody detects endogenous levels of BMP-5 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
52kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human BMP-5. AA range:114-163
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Specificity:
BMP-5 Polyclonal Antibody detects endogenous levels of BMP-5 protein.
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Gene Name:
BMP5
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Protein Name:
Bone morphogenetic protein 5
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Other Name:
BMP5 ;
Bone morphogenetic protein 5 ;
BMP-5
Bone morphogenetic protein 5 ;
BMP-5
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Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016],
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Function:
Function:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 5 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed in the lung and liver.,
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Cellular Localization:
Secreted.
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Tissue Expression:
Expressed in the lung and liver.
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Research Areas:
>>Cytokine-cytokine receptor interaction ;
>>TGF-beta signaling pathway ;
>>Hippo signaling pathway
>>TGF-beta signaling pathway ;
>>Hippo signaling pathway
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT0501
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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