The antiserum was produced against synthesized peptide derived from human ADRB3. AA range:250-299

AR-β3 Polyclonal Antibody detects endogenous levels of AR-β3 protein.

ADRB3

Beta-3 adrenergic receptor

ADRB3 ;
ADRB3R ;
B3AR ;
Beta-3 adrenergic receptor ;
Beta-3 adrenoreceptor ;
Beta-3 adrenoceptor

The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. [provided by RefSeq, Feb 2009],

Function:Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.,polymorphism:The variant Arg-64 seems to be associated with weight gain (obesity) and to is also associated with susceptibility to non-insulin-dependent diabetes mellitus (NIDDM).,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed mainly in adipose tissues.,

Cell membrane; Multi-pass membrane protein.

Expressed mainly in adipose tissues.

>>Calcium signaling pathway ;
>>cGMP-PKG signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Thermogenesis ;
>>Regulation of lipolysis in adipocytes ;
>>Renin secretion ;
>>Salivary secretion ;
>>Chemical carcinogenesis - receptor activation