This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],
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Function:
Function:Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR2 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with SQSTM1 (By similarity). Binds DNA as a homodimer.,tissue specificity:Found in all tissues.,
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Cellular Localization:
Nucleus.
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Tissue Expression:
Ubiquitous. Expressed in the stromal cells of developing fetal ovaries (PubMed:29478779).