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AKAP 110 Rabbit pAb

-YT0160

Catalog: YT0160
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Collected

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Main Information
Target

AKAP 110

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

IF, ELISA

MW

95kD (Calculated)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications;
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
AKAP 110 Polyclonal Antibody detects endogenous levels of AKAP 110 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
95kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human AKAP3. AA range:191-240
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Specificity:
AKAP 110 Polyclonal Antibody detects endogenous levels of AKAP 110 protein.
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Gene Name:
AKAP3
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Protein Name:
A-kinase anchor protein 3
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Other Name:
AKAP3 ;
AKAP110 ;
SOB1 ;
A-kinase anchor protein 3 ;
AKAP-3 ;
A-kinase anchor protein 110 kDa ;
AKAP 110 ;
Cancer/testis antigen 82 ;
CT82 ;
Fibrous sheath protein of 95 kDa ;
FSP95 ;
Fibrousheathin I ;
Fibrousheathin-1 ;
Protein kinase A-anchoring prot
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Database Link:
Organism Gene ID SwissProt
Human 10566; O75969;
Mouse 11642; O88987;
Background:
This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is reported to participate in protein-protein interactions with the R-subunit of the protein kinase A as well as sperm-associated proteins. This protein is expressed in spermatozoa and localized to the acrosomal region of the sperm head as well as the length of the principal piece. It may function as a regulator of motility, capacitation, and the acrosome reaction. [provided by RefSeq, May 2013],
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Function:
Domain:RII-binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,Function:May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.,PTM:Phosphorylated on tyrosine residues.,similarity:Belongs to the AKAP110 family.,subcellular location:Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.,subunit:Interacts with ROPN1 AND ROPN1L.,tissue specificity:Testis specific; only expressed in spermatids.,
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Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, acrosome . Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment.
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Catalog: YT0160
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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