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Catalog: YT0050
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

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Main Information
Target

ABCD4

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB, IHC, IF, ELISA

MW

70kD (Observed)

Conjugate/Modification


Unmodified

Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
ABCD4 Polyclonal Antibody detects endogenous levels of ABCD4 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
70kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human ABCD4. AA range:111-160
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Specificity:
ABCD4 Polyclonal Antibody detects endogenous levels of ABCD4 protein.
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Gene Name:
ABCD4
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Protein Name:
ATP-binding cassette sub-family D member 4
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Other Name:
ABCD4 ;
PXMP1L ;
ATP-binding cassette sub-family D member 4 ;
PMP70-related protein ;
P70R ;
Peroxisomal membrane protein 1-like ;
PXMP1-L ;
Peroxisomal membrane protein 69 ;
PMP69
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Database Link:
Organism Gene ID SwissProt
Human 5826; O14678;
Mouse 19300; O89016;
Background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxi
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Function:
similarity:Belongs to the ABC transporter family. ALD subfamily.,similarity:Contains 1 ABC transmembrane type-1 domain.,similarity:Contains 1 ABC transporter domain.,subunit:Homodimer or heterodimer .,tissue specificity:Ubiquitous.,
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Cellular Localization:
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Targeted by LMBRD1 lysosomal chaperone to the lysosomal membrane. .
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Tissue Expression:
Ubiquitous.
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Research Areas:
>>ABC transporters ;
>>Peroxisome
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Catalog: YT0050
Size
Price
Status
Qty.
200μL
$450.00
In stock

0

100μL
$280.00
In stock

0

40μL
$150.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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