Catalog: YT0028
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
9G8
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
35kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
9G8 Polyclonal Antibody detects endogenous levels of 9G8 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
35kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human SFRS7. AA range:61-110
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Specificity:
9G8 Polyclonal Antibody detects endogenous levels of 9G8 protein.
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Gene Name:
SRSF7
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Protein Name:
Serine/arginine-rich splicing factor 7
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Other Name:
SRSF7 ;
SFRS7 ;
Serine/arginine-rich splicing factor 7 ;
Splicing factor 9G8 ;
Splicing factor ;
arginine/serine-rich 7
SFRS7 ;
Serine/arginine-rich splicing factor 7 ;
Splicing factor 9G8 ;
Splicing factor ;
arginine/serine-rich 7
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Background:
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010],
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Function:
Alternative products:Isoforms, often lacking the RS domain and differentially expressed in fetal tissues, may be involved in modulation of 9G8 function,Function:Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 CCHC-type zinc finger.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Found in large molecular weight complexes containing CCNL1 and the p110 isoforms of either CDC2L1 or CDC2L2. Interacts with CCNL2 and CPSF6.,tissue specificity:Brain, liver, kidney and lung.,
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Cellular Localization:
Nucleus . Cytoplasm .
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Tissue Expression:
Brain, liver, kidney and lung.
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Research Areas:
>>Spliceosome ;
>>Amyotrophic lateral sclerosis ;
>>Herpes simplex virus 1 infection
>>Amyotrophic lateral sclerosis ;
>>Herpes simplex virus 1 infection
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Reference Citation({{totalcount}})
Catalog: YT0028
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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