Catalog: YN3960
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
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Main Information
Target
PRCC
Host Species
Rabbit
Reactivity
Human
Applications
WB
MW
54kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of PRCC at Human
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
54kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PRCC AA range: 74-124
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Specificity:
This antibody detects endogenous levels of PRCC at Human
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Gene Name:
PRCC TPRC
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Protein Name:
PRCC
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Background:
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010],
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Function:
Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,Disease:A chromosomal aberration involving PRCC may be a cause of papillary renal cell carcinoma (PRCC) [MIM:605074]. Translocation t(X;1)(p11.2;q21.2) with TFE3.,tissue specificity:Ubiquitous in fetal and adult tissues.,
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Cellular Localization:
Nucleus .
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Tissue Expression:
Ubiquitous in fetal and adult tissues.
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Research Areas:
>>Transcriptional misregulation in cancer ;
>>Renal cell carcinoma
>>Renal cell carcinoma
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN3960
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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