Catalytic activity:ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.,Catalytic activity:CDP-choline + H(2)O = CMP + phosphocholine.,Catalytic activity:CDP-glycerol + H(2)O = CMP + sn-glycerol 3-phosphate.,cofactor:Magnesium.,Function:hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress.,similarity:Belongs to the ADPRibase-Mn family.,subunit:Monomer.,