Catalog: YN3405
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
YMEL1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
82kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of PACE1 at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
82kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PACE1 AA range: 519-569
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Specificity:
This antibody detects endogenous levels of PACE1 at Human/Mouse
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Gene Name:
SCYL3 PACE1
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Protein Name:
PACE1
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Background:
This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012],
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Function:
Domain:The protein kinase domain is predicted to be catalytically inactive.,Function:May play a role in regulating cell adhesion/migration complexes in migrating cells.,PTM:May be myristoylated; myristoylation may target it to Golgi compartment.,PTM:Phosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 4 HEAT repeats.,subcellular location:Colocalized with EZR/VIL2, actin and CD44 in lamellipodia.,subunit:Interacts with EZR/VIL2 C-terminal domain.,tissue specificity:Ubiquitously expressed.,
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Cellular Localization:
Cytoplasm . Golgi apparatus . Cell projection, lamellipodium . Colocalized with EZR/VIL2, actin and CD44 in lamellipodia.
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Tissue Expression:
Ubiquitously expressed.
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Reference Citation({{totalcount}})
Catalog: YN3405
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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