Catalog: YN3315
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
IPO13
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
105kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of PP6R2 at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
105kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PP6R2 AA range: 59-109
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Specificity:
This antibody detects endogenous levels of PP6R2 at Human/Mouse
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Gene Name:
PPP6R2 KIAA0685 PP6R2 SAPS2
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Protein Name:
PP6R2
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Other Name:
Serine/threonine-protein phosphatase 6 regulatory subunit 2 ;
SAPS domain family member 2 ;
SAPS domain family member 2 ;
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Background:
Protein phosphatase regulatory subunits, such as SAPS2, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS2 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010],
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Function:
Function:Regulatory subunit of protein phospatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.,similarity:Belongs to the SAPS family.,subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP6C and NFKBIE. Interacts with ANKRD28.,tissue specificity:Ubiquitously expressed with strongest expression in the testis followed by liver, heart, kidney, brain and placenta.,
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Cellular Localization:
Cytoplasm .
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Tissue Expression:
Ubiquitously expressed with strongest expression in the testis followed by liver, heart, kidney, brain and placenta.
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Reference Citation({{totalcount}})
Catalog: YN3315
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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