Catalog: YN3306
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
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0
40μL
$150.00
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Main Information
Target
RBM19
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
105kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of IQEC1 at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
105kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human IQEC1 AA range: 693-743
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Specificity:
This antibody detects endogenous levels of IQEC1 at Human/Mouse
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Gene Name:
IQSEC1 ARFGEP100 BRAG2 KIAA0763
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Protein Name:
IQEC1
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Other Name:
IQ motif and SEC7 domain-containing protein 1 ;
ADP-ribosylation factors guanine nucleotide-exchange protein 100 ;
ADP-ribosylation factors guanine nucleotide-exchange protein 2 ;
Brefeldin-resistant Arf-GEF 2 protein ;
ADP-ribosylation factors guanine nucleotide-exchange protein 100 ;
ADP-ribosylation factors guanine nucleotide-exchange protein 2 ;
Brefeldin-resistant Arf-GEF 2 protein ;
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Function:
Function:In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.,similarity:Belongs to the BRAG family.,similarity:Contains 1 IQ domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SEC7 domain.,subcellular location:At steady state, may be preferentially cytosolic.,subunit:Interacts with ARF6.,tissue specificity:Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis.,
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Cellular Localization:
Cytoplasm . Nucleus . Cell junction, synapse, postsynaptic density . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . At steady state, may be preferentially cytosolic.
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Tissue Expression:
Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis.
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Research Areas:
>>Endocytosis
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Reference Citation({{totalcount}})
Catalog: YN3306
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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