Catalog: YN3185
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
INSM2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
60kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of LCTL at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
60kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human LCTL AA range: 450-500
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Specificity:
This antibody detects endogenous levels of LCTL at Human/Mouse
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Gene Name:
LCTL KLPH UNQ3022/PRO9820
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Protein Name:
LCTL
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Other Name:
Lactase-like protein ;
Klotho/lactase-phlorizin hydrolase-related protein ;
Klotho/lactase-phlorizin hydrolase-related protein ;
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Background:
This gene encodes a member of family 1 glycosidases. Glycosidases are enzymes that hydrolyze glycosidic bonds and are classified into families based on primary amino acid sequence. Most members of family 1 have two conserved glutamic acid residues, which are required for enzymatic activity. The mouse ortholog of this protein has been characterized and has a domain structure of an N-terminal signal peptide, glycosidase domain, transmembrane domain, and a short cytoplasmic tail. It lacks one of the conserved glutamic acid residues important for catalysis, and its function remains to be determined (PMID: 12084582). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
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Function:
Caution:Probably inactive as a glycosidase since it lacks the essential active site Glu at position 201.,similarity:Belongs to the glycosyl hydrolase 1 family.,similarity:Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.,
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Cellular Localization:
Endoplasmic reticulum membrane ; Single-pass membrane protein .
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Reference Citation({{totalcount}})
Catalog: YN3185
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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