Catalog: YN3100
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
MBNL3
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
38kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of MBNL3 at Human/Mouse
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
38kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human MBNL3 AA range: 184-234
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Specificity:
This antibody detects endogenous levels of MBNL3 at Human/Mouse
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Gene Name:
MBNL3 CHCR MBLX39 MBXL
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Protein Name:
MBNL3
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Other Name:
Muscleblind-like protein 3 ;
Cys3His CCG1-required protein ;
Muscleblind-like X-linked protein ;
Protein HCHCR ;
Cys3His CCG1-required protein ;
Muscleblind-like X-linked protein ;
Protein HCHCR ;
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Background:
This gene encodes a member of the muscleblind-like family of proteins. The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009],
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Function:
Function:Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.,similarity:Belongs to the muscleblind family.,similarity:Contains 4 C3H1-type zinc fingers.,subcellular location:Greater concentration in the nucleus. In both myotonic dystrophy 1 (DM1) and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.,tissue specificity:Highly expressed in the placenta.,
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Cellular Localization:
Nucleus . Cytoplasm . Greater concentration in the nucleus. In both DM1 and DM2 patients, colocalizes with nuclear foci of retained expanded-repeat transcripts.
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Tissue Expression:
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Reference Citation({{totalcount}})
Catalog: YN3100
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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