Catalog: YN2990
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
RFA4
Host Species
Rabbit
Reactivity
Human
Applications
WB, ELISA
MW
28kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
RFA4 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
28kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
RFA4 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
RPA4
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Protein Name:
Replication protein A 30 kDa subunit (RP-A p30) (Replication factor A protein 4) (RF-A protein 4)
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Background:
This gene encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.[provided by RefSeq, Apr 2010],
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Function:
Function:Absolutely required for simian virus 40 DNA replication in vitro. It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein.,subunit:Interacts with RPA1 and RPA3. In a tissue-specic manner, may replace RPA2 in the replication protein A heterotrimer.,tissue specificity:Preferentially expressed in placental and colon mucosa.,
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Cellular Localization:
Nucleus . Localizes to DNA repair foci after DNA damage.
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Tissue Expression:
Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels.
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Research Areas:
>>DNA replication ;
>>Nucleotide excision repair ;
>>Mismatch repair ;
>>Homologous recombination ;
>>Fanconi anemia pathway
>>Nucleotide excision repair ;
>>Mismatch repair ;
>>Homologous recombination ;
>>Fanconi anemia pathway
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Reference Citation({{totalcount}})
Catalog: YN2990
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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