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Main Information
Target
ANFC
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
13kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
ANFC Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
13kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 65-95
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Specificity:
ANFC Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
NPPC CNP2
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Protein Name:
C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]
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Background:
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients. [provided by RefSeq, Oct 2015],
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Function:
Function:Vasorelaxant activity. Has a cGMP-stimulating activity.,similarity:Belongs to the natriuretic peptide family.,
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Cellular Localization:
Secreted.
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Tissue Expression:
[CNP-22]: In the kidney, predominantly expressed in the distal tubular cells (at protein level).
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Research Areas:
>>cGMP-PKG signaling pathway ;
>>Vascular smooth muscle contraction ;
>>Fluid shear stress and atherosclerosis
>>Vascular smooth muscle contraction ;
>>Fluid shear stress and atherosclerosis
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Catalog: YN2864
Size
Price
Status
Qty.
200μL
$450.00
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0
100μL
$280.00
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40μL
$150.00
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0
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