Catalog: YN2673
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
P2RY1
Host Species
Rabbit
Reactivity
Human, Rat, Mouse
Applications
WB, ELISA
MW
41kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
P2RY1 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
41kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
RRID
AB_2936921
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 130-210
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Specificity:
P2RY1 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
P2RY1
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Protein Name:
P2Y purinoceptor 1 (P2Y1) (ATP receptor) (Purinergic receptor)
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Background:
purinergic receptor P2Y1(P2RY1) Homo sapiens The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008],
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Function:
Function:Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.,induction:Repressed by the P2Y1 receptor-specific antagonists A3P5PS, A3P5P and A2P5P. These inhibit calcium ion mobilization and shape change in platelets.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein .
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Tissue Expression:
Blood,Brain,Lung,Placenta,Platelet,
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Research Areas:
>>Rap1 signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Platelet activation ;
>>Taste transduction
>>Neuroactive ligand-receptor interaction ;
>>Platelet activation ;
>>Taste transduction
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YN2673
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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