Catalog: YN1965
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
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Main Information
Target
OPT
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
36kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Specificity
OPT Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
36kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from part region of human protein
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Specificity:
OPT Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
OPTC OPT
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Protein Name:
Opticin (Oculoglycan)
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Background:
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1). [provided by RefSeq, Jul 2008],
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Function:
Function:Binds collagen fibrils.,PTM:O-glycosylated.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class III subfamily.,similarity:Contains 7 LRR (leucine-rich) repeats.,tissue specificity:Retina, iris, ligament, skin and fetal liver.,
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Cellular Localization:
Secreted, extracellular space, extracellular matrix .
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Tissue Expression:
Expressed in cartilage and synovial membranes (at protein level) (PubMed:18164633, PubMed:23845380). Expressed in the retina, iris, ligament, skin and fetal liver (at protein level) (PubMed:12019215, PubMed:25136834). Expressed in the retinal pigment epithelium (at protein level) (PubMed:25136834). Expressed in synovial fibroblasts and subchondral bone osteoblasts (PubMed:18164633).
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Reference Citation({{totalcount}})
Catalog: YN1965
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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