Catalog: YN1230
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
RND2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
24kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
RND2 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
24kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 140-220
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Specificity:
RND2 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
RND2 ARHN RHO7
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Protein Name:
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
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Background:
This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008],
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Function:
Function:May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily.,similarity:Belongs to the small GTPase superfamily. Rho family.,subcellular location:Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome.,subunit:Interacts with the Rho-GAP domain of RACGAP1. Interacts with UBXD5.,tissue specificity:Highly expressed in testis.,
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Cellular Localization:
Cytoplasmic vesicle, secretory vesicle, acrosome membrane ; Lipid-anchor ; Cytoplasmic side . Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome. .
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Tissue Expression:
Highly expressed in testis.
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Reference Citation({{totalcount}})
Catalog: YN1230
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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