This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008],
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Function:
similarity:Belongs to the IAN GTP-binding protein family.,
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Cellular Localization:
Lipid droplet . Cytoplasm . Endoplasmic reticulum . Golgi apparatus . Colocalizes with GIMAP2 on the surface of cytoplasmic lipid droplets.
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Tissue Expression:
Most abundantly expressed in spleen, lymph nodes, and fetal kidney, but also present in the heart and the small intestine. Lower expression levels are found in lung, kidney, liver, and thyroid, salivary, and mammary glands. Also detected in the thymus (PubMed:15474311). Detected in T-cells (PubMed:23454188).