Endogenous

FABP4

A-FABP

Fatty acid-binding protein, adipocyte ;
Adipocyte lipid-binding protein ;
ALBP ;
Adipocyte-type fatty acid-binding protein ;
A-FABP ;
AFABP ;
Fatty acid-binding protein 4 ;

FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008],

Domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,Function:Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,subcellular location:Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.,subunit:Homodimer. Interacts with PPARG (By similarity). Monomer.,

Cytoplasm

>>PPAR signaling pathway ;
>>Regulation of lipolysis in adipocytes