Catalog: YM4697
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
HMGB1
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ELISA
MW
25kD (Calculated)
24kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
This antibody detects endogenous levels of HMGB1 protein.
Purification
Protein G
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
25kD
MW(Observed)
24kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PTR2339
Isotype
IgG1,Kappa
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human HMGB1 AA range: 100-200
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Specificity:
This antibody detects endogenous levels of HMGB1 protein.
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Gene Name:
HMGB1 HMG1
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Protein Name:
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
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Other Name:
High mobility group protein B1 ;
High mobility group protein 1 ;
HMG-1 ;
High mobility group protein 1 ;
HMG-1 ;
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Database Link:
Background:
high mobility group box 1(HMGB1) Homo sapiens This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015],
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Function:
Function:Binds preferentially single-stranded DNA and unwinds double stranded DNA.,similarity:Belongs to the HMGB family.,similarity:Contains 2 HMG box DNA-binding domains.,
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Tissue Expression:
Research Areas:
>>Base excision repair ;
>>Autophagy - animal ;
>>Necroptosis ;
>>Neutrophil extracellular trap formation
>>Autophagy - animal ;
>>Necroptosis ;
>>Neutrophil extracellular trap formation
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM4697
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$160.00
In stock
0
Add to cart
Collected
Collect
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