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Tubulin α (Acetyl Lys40) (5H5) Mouse mAb

-YM3585

Main Information
Target

Tubulin α

Host Species

Mouse

Reactivity

Human, Rat, Mouse

Applications

WB, IHC, IF

MW

52kD (Observed)

Conjugate/Modification


Acetyl

Detailed Information
Recommended Dilution Ratio
WB 1:1000-2000; IHC 1:100-200; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
α-tubulin (Acetyl Lys40) protein detects endogenous levels of α-tubulin (Acetyl Lys40)
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
52kD
Modification
Acetyl
Clonality
Monoclonal
Clone Number
5H5
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Secondary Antibodies
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Antigen&Target Information
Immunogen:
Synthetic Peptide of α-tubulin (Acetyl Lys40)
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Specificity:
α-tubulin (Acetyl Lys40) protein detects endogenous levels of α-tubulin (Acetyl Lys40)
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Gene Name:
TUBA1B
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Protein Name:
Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain)
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Other Name:
Tubulin alpha-1B chain ;
Alpha-tubulin ubiquitous ;
Tubulin K-alpha-1 ;
Tubulin alpha-ubiquitous chain ;
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Database Link:
Organism Gene ID SwissProt
Human 7277; P68363;
Mouse P05213;
Rat Q6P9V9;
Background:
function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
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Function:
Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
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Cellular Localization:
Cytoplasm, cytoskeleton.
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Tissue Expression:
Brain,Cajal-Retzius cell,Colon,Embryonic kidney,Eye,Fetal brain cortex,Keratinocyte
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Research Areas:
>>Phagosome ;
>>Apoptosis ;
>>Tight junction ;
>>Gap junction ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Pathogenic Escherichia coli infection ;
>>Salmonella infection
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