Catalog: YM0303
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
Add to cart
Collected
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Main Information
Target
GDF-8
Host Species
Mouse
Reactivity
Human
Applications
WB, ELISA
MW
43kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
GDF-8 Monoclonal Antibody detects endogenous levels of GDF-8 protein.
Purification
Affinity purification
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Calculated)
43kD
Modification
Unmodified
Clonality
Monoclonal
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Antigen&Target Information
Immunogen:
Purified recombinant fragment of GDF-8 expressed in E. Coli.
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Specificity:
GDF-8 Monoclonal Antibody detects endogenous levels of GDF-8 protein.
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Gene Name:
MSTN
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Protein Name:
Growth/differentiation factor 8
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Other Name:
MSTN ;
GDF8 ;
Growth/differentiation factor 8 ;
GDF-8 ;
Myostatin
GDF8 ;
Growth/differentiation factor 8 ;
GDF-8 ;
Myostatin
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Background:
myostatin(MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],
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Function:
Function:Acts specifically as a negative regulator of skeletal muscle growth.,online information:Myostatin entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked (By similarity). Interacts with WFIKKN2, leading to inhibit its activity.,
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Cellular Localization:
Secreted .
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Tissue Expression:
Colon,Muscle,Pericardium,Skeletal muscle,
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Research Areas:
>>Cytokine-cytokine receptor interaction
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM0303
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$350.00
3 weeks
0
50μL
$210.00
3 weeks
0
Add to cart
Collected
Collect
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