Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of Human,Mouse PPGB (20k, Cleaved-Met327, protein was cleaved amino acid sequence between 326-327 )
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
20kD,52kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PPGB (20k, Cleaved-Met327)
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Specificity:
This antibody detects endogenous levels of Human,Mouse PPGB (20k, Cleaved-Met327, protein was cleaved amino acid sequence between 326-327 )
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Gene Name:
CTSA PPGB
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Protein Name:
Lysosomal protective protein (20k, Cleaved-Met327)
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Other Name:
CTSA ;
PPGB ;
Lysosomal protective protein ;
Carboxypeptidase C ;
Carboxypeptidase L ;
Cathepsin A ;
Protective protein cathepsin A ;
PPCA ;
Protective protein for beta-galactosidase ;
[Cleaved into: Lysosomal protective protein 32 kDa chain ;
Lysosomal protective protein 20 kDa chain]
catalytic activity:Release of a C-terminal amino acid with broad specificity.,disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease.,function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.,similarity:Belongs to the peptidase S10 family.,subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.,
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Function:
proteolysis, intracellular protein transport, protein localization, protein transport, cellular protein localization,establishment of protein localization, intracellular transport, cellular macromolecule localization,