Catalog: YF0116
Size
Price
Status
Qty.
10mg
$0.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
IL-8RA
Host Species
Mouse
Reactivity
Human
Applications
FC
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
Formulation
PBS, pH 7.4
Specificity
Endogenous
Purification
Protein A
Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Concentration
0.5mg/ml
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PTF0106
Isotype
Mouse IgG2b/Kappa
Related Products
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
More→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
More→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
More→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
More→
Antigen&Target Information
Specificity:
Endogenous
show all
Gene Name:
CXCR1 CMKAR1 IL8RA
show all
Protein Name:
C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181)
show all
Other Name:
C-X-C chemokine receptor type 1 ;
CXC-R1 ;
CXCR-1 ;
CDw128a ;
High affinity interleukin-8 receptor A ;
IL-8R A ;
IL-8 receptor type 1 ;
CD antigen CD181 ;
CXC-R1 ;
CXCR-1 ;
CDw128a ;
High affinity interleukin-8 receptor A ;
IL-8R A ;
IL-8 receptor type 1 ;
CD antigen CD181 ;
show all
Background:
C-X-C motif chemokine receptor 1(CXCR1) Homo sapiens The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008],
show all
Function:
Function:Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.,online information:CXC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,
show all
Cellular Localization:
Cell membrane; Multi-pass membrane protein.
show all
Tissue Expression:
show all
Research Areas:
>>Cytokine-cytokine receptor interaction ;
>>Viral protein interaction with cytokine and cytokine receptor ;
>>Chemokine signaling pathway ;
>>Phospholipase D signaling pathway ;
>>Endocytosis ;
>>Epithelial cell signaling in Helicobacter pylori infection
>>Viral protein interaction with cytokine and cytokine receptor ;
>>Chemokine signaling pathway ;
>>Phospholipase D signaling pathway ;
>>Endocytosis ;
>>Epithelial cell signaling in Helicobacter pylori infection
show all
Signaling Pathway
Organismal Systems >> Immune system >> Chemokine signaling pathway
Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
Reference Citation({{totalcount}})
Catalog: YF0116
Size
Price
Status
Qty.
10mg
$0.00
3 weeks
0
Add to cart
Collected
Collect
Recently Viewed Products
Clear allPRODUCTS
CUSTOMIZED
ABOUT US
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Product {{index}}/{{pcount}}
Prev
Next
{{pvTitle}}
Scroll wheel zooms the picture
{{pvDescr}}