Catalog: YT6364
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Collected
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Main Information
Target
SHOX2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, Flow Cyt
MW
36kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IHC 1:50-300,Flow Cyt 1:100-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of SHOX2 at Human/Mouse/Rat
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
36kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human SHOX2 AA range: 37-87
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Specificity:
This antibody detects endogenous levels of SHOX2 at Human/Mouse/Rat
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Gene Name:
SHOX2 OG12X SHOT
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Protein Name:
SHOX2
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Database Link:
Background:
This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],
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Function:
developmental stage:Expressed during cranofacial development as well as in heart.,Function:May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation.,similarity:Belongs to the paired homeobox family. Bicoid subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,tissue specificity:Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta.,
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Cellular Localization:
Nucleus.
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Tissue Expression:
Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta.
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Reference Citation({{totalcount}})
Catalog: YT6364
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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