Catalog: YT5447
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
EP1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
44kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
EP1 Polyclonal Antibody detects endogenous levels of EP1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
44kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human PTGER1. AA range:191-240
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Specificity:
EP1 Polyclonal Antibody detects endogenous levels of EP1 protein.
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Gene Name:
PTGER1
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Protein Name:
Prostaglandin E2 receptor EP1 subtype
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Other Name:
PTGER1 ;
Prostaglandin E2 receptor EP1 subtype ;
PGE receptor EP1 subtype ;
PGE2 receptor EP1 subtype ;
Prostanoid EP1 receptor
Prostaglandin E2 receptor EP1 subtype ;
PGE receptor EP1 subtype ;
PGE2 receptor EP1 subtype ;
Prostanoid EP1 receptor
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Background:
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008],
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Function:
Function:Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.,PTM:Phosphorylated .,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart.,
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Tissue Expression:
Research Areas:
>>Calcium signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Human cytomegalovirus infection ;
>>Pathways in cancer
>>Neuroactive ligand-receptor interaction ;
>>Human cytomegalovirus infection ;
>>Pathways in cancer
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YT5447
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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