The antiserum was produced against synthesized peptide derived from the N-terminal region of human GORAB. AA range:1-50

SCYL1BP1 Polyclonal Antibody detects endogenous levels of SCYL1BP1 protein.

GORAB

RAB6-interacting golgin

GORAB ;
NTKLBP1 ;
SCYL1BP1 ;
RAB6-interacting golgin ;
N-terminal kinase-like-binding protein 1 ;
NTKL-BP1 ;
NTKL-binding protein 1 ;
hNTKL-BP1 ;
SCY1-like 1-binding protein 1 ;
SCYL1-BP1 ;
SCYL1-binding protein 1

golgin, RAB6 interacting(GORAB) Homo sapiens This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009],

Caution:It is uncertain whether Met-1 or Met-26 is the initiator.,Disease:Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.,similarity:Belongs to the GORAB family.,subunit:Interacts with SCYL1 (By similarity). Interacts with RCHY1 and RAB6A/RAB6.,

Cytoplasm . Golgi apparatus .

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