The antiserum was produced against synthesized peptide derived from the Internal region of human FCGR2B/C. AA range:141-190

CD32-B/C Polyclonal Antibody detects endogenous levels of CD32-B/C protein.

FCGR2B/FCGR2C

Low affinity immunoglobulin gamma Fc region receptor II-b/Low affinity immunoglobulin gamma Fc region receptor II-c

FCGR2B ;
CD32 ;
FCG2 ;
IGFR2 ;
Low affinity immunoglobulin gamma Fc region receptor II-b ;
IgG Fc receptor II-b ;
CDw32 ;
Fc-gamma RII-b ;
Fc-gamma-RIIb ;
FcRII-b ;
CD32 ;
FCGR2C ;
CD32 ;
FCG2 ;
IGFR2 ;
Low affinity immunoglobulin gamma Fc region receptor II-c ;
IgG Fc receptor II-c ;
CDw32 ;
Fc-gamma RII-c ;
Fc-gamma-RIIc ;
FcRII-c ;
CD32

Low affinity immunoglobulin gamma Fc region receptor II-b/Low affinity immunoglobulin gamma Fc region receptor II-c encoded by FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

immune response,

Cell membrane; Single-pass type I membrane protein.

Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.

>>Phagosome ;
>>Osteoclast differentiation ;
>>B cell receptor signaling pathway ;
>>Fc gamma R-mediated phagocytosis ;
>>Staphylococcus aureus infection ;
>>Tuberculosis ;
>>Measles