Catalog: YT1592
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
Ephrin-A4
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
95kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
Ephrin-A4 Polyclonal Antibody detects endogenous levels of Ephrin-A4 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
95kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human EFNA4. AA range:131-180
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Specificity:
Ephrin-A4 Polyclonal Antibody detects endogenous levels of Ephrin-A4 protein.
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Gene Name:
EFNA4 EPLG4 LERK4
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Protein Name:
Ephrin-A4
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Other Name:
EFNA4 ;
EPLG4 ;
LERK4 ;
Ephrin-A4 ;
EPH-related receptor tyrosine kinase ligand 4 ;
LERK-4
EPLG4 ;
LERK4 ;
Ephrin-A4 ;
EPH-related receptor tyrosine kinase ligand 4 ;
LERK-4
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Background:
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified. [provided by RefSeq, Jul 2008],
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Function:
Function:May play a role in the interaction between activated B lymphocytes and dendritic cells in tonsils.,similarity:Belongs to the ephrin family.,tissue specificity:Expressed in the adult spleen, lymph node, prostate, ovary, small intestine, and colon, and in fetal heart, lung, liver and kidney. Also detected in hematopoietic cell lines.,
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Cellular Localization:
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 2]: Secreted .
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Tissue Expression:
Research Areas:
>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Axon guidance ;
>>MicroRNAs in cancer
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Axon guidance ;
>>MicroRNAs in cancer
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Signaling Pathway
Human Diseases >> Cancer: overview >> MicroRNAs in cancer
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Reference Citation({{totalcount}})
Catalog: YT1592
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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