The antiserum was produced against synthesized peptide derived from human EFNA1. AA range:66-115

Ephrin-A1 Polyclonal Antibody detects endogenous levels of Ephrin-A1 protein.

EFNA1 EPLG1 LERK1 TNFAIP4

Ephrin-A1

EFNA1 ;
EPLG1 ;
LERK1 ;
TNFAIP4 ;
Ephrin-A1 ;
EPH-related receptor tyrosine kinase ligand 1 ;
LERK-1 ;
Immediate early response protein B61 ;
Tumor necrosis factor alpha-induced protein 4 ;
TNF alpha-induced protein 4 ;
[Cleaved into: Ephrin-A1, secreted form]

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008],

induction:By TNF-alpha and interleukin-1 beta.,similarity:Belongs to the ephrin family.,subunit:Binds to the receptor tyrosine kinases EPHA2, EPHA4, EPHA5, EPHA6 and EPHA7. Also binds with low affinity to EPHA1.,

Cell membrane ; Lipid-anchor, GPI-anchor .; [Ephrin-A1, secreted form]: Secreted .

>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Axon guidance ;
>>MicroRNAs in cancer