The antiserum was produced against synthesized peptide derived from human FCGR2A. AA range:241-290

CD32-A Polyclonal Antibody detects endogenous levels of CD32-A protein.

FCGR2A

Low affinity immunoglobulin gamma Fc region receptor II-a

FCGR2A ;
CD32 ;
FCG2 ;
FCGR2A1 ;
IGFR2 ;
Low affinity immunoglobulin gamma Fc region receptor II-a ;
IgG Fc receptor II-a ;
CDw32 ;
Fc-gamma RII-a ;
Fc-gamma-RIIa ;
FcRII-a ;
CD antigen CD32

Fc fragment of IgG receptor IIa(FCGR2A) Homo sapiens This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008],

Function:Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with INPP5D/SHIP1 and INPPL1/SHIP2, regulating its function.,tissue specificity:Found on monocytes, neutrophils and eosinophil platelets.,

Cell membrane ; Single-pass type I membrane protein .

>>Phagosome ;
>>Osteoclast differentiation ;
>>Platelet activation ;
>>Neutrophil extracellular trap formation ;
>>Fc gamma R-mediated phagocytosis ;
>>Pathogenic Escherichia coli infection ;
>>Yersinia infection ;
>>Leishmaniasis ;
>>Staphylococcus aureus infection ;
>>Tuberculosis ;
>>Coronavirus disease - COVID-19 ;
>>Systemic lupus erythematosus