Catalog: YT0357
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
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Main Information
Target
AR-α1D
Host Species
Rabbit
Reactivity
Human, Rat, Mouse,
Applications
IHC, IF, ELISA
MW
60kD (Calculated)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
AR-α1D Polyclonal Antibody detects endogenous levels of AR-α1D protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Calculated)
60kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
The antiserum was produced against synthesized peptide derived from human ADRA1D. AA range:451-500
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Specificity:
AR-α1D Polyclonal Antibody detects endogenous levels of AR-α1D protein.
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Gene Name:
ADRA1D
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Protein Name:
Alpha-1D adrenergic receptor
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Other Name:
ADRA1D ;
ADRA1A ;
Alpha-1D adrenergic receptor ;
Alpha-1A adrenergic receptor ;
Alpha-1D adrenoreceptor ;
Alpha-1D adrenoceptor ;
Alpha-adrenergic receptor 1a
ADRA1A ;
Alpha-1D adrenergic receptor ;
Alpha-1A adrenergic receptor ;
Alpha-1D adrenoreceptor ;
Alpha-1D adrenoceptor ;
Alpha-adrenergic receptor 1a
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Background:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008],
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Function:
Function:This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.,similarity:Belongs to the G-protein coupled receptor 1 family.,
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Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Tissue Expression:
Hippocampus,Placenta,Prostate,
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Research Areas:
>>Calcium signaling pathway ;
>>cGMP-PKG signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Adrenergic signaling in cardiomyocytes ;
>>Vascular smooth muscle contraction ;
>>Salivary secretion
>>cGMP-PKG signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Adrenergic signaling in cardiomyocytes ;
>>Vascular smooth muscle contraction ;
>>Salivary secretion
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Signaling Pathway
Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes
Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction
Environmental Information Processing >> Signal transduction >> Calcium signaling pathway
Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
Reference Citation({{totalcount}})
Catalog: YT0357
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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