Catalog: YN1226
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
Main Information
Target
RND1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA
MW
25kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Specificity
RND1 Polyclonal Antibody detects endogenous levels of protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
MW(Observed)
25kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human protein . at AA range: 140-220
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Specificity:
RND1 Polyclonal Antibody detects endogenous levels of protein.
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Gene Name:
RND1 RHO6
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Protein Name:
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
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Background:
This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014],
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Function:
Function:Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Binds GRB7 and PLXNB1. Interacts with UBXD5.,tissue specificity:Mostly expressed in brain and liver.,
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Cellular Localization:
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytoskeleton .
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Tissue Expression:
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Research Areas:
>>Axon guidance
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Reference Citation({{totalcount}})
Catalog: YN1226
Size
Price
Status
Qty.
200μL
$450.00
In stock
0
100μL
$280.00
In stock
0
40μL
$150.00
In stock
0
Add to cart
Collected
Collect
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